Funding Opportunities

HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (Independent Basic Experimental Studies with Humans Required) 

The purpose of this K99/R00 program is to support a cohort of new and talented independent investigators conducting Pain and/or SUD research, in order to increase the independent investigator workforce in research areas supported by the NIH HEAL InitiativeSM. This program is designed to facilitate a timely transition of eligible outstanding postdoctoral researchers from their mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition to help awardees establish independent research programs in areas supported by the NIH HEAL InitiativeSM. 

Deadline: Standard dates apply. This opportunity expires March 12, 2025.

NOSI: Public Health Research on Cannabis 

Policies around of cannabis products (including whole plant cannabis and cannabis constituent compounds) in the United States (and globally) continue to evolve, and far outpace the knowledge needed to determine the public health impacts of these changes. Growing numbers of states have loosened restrictions on cannabis, including those on sales and use, by passing medical cannabis laws or by making cannabis legal for adult recreational use, and in increasing numbers, states have done both. Recognizing this widening research gap, in 2018 NIDA sought input from a  National Advisory Council on Drug Abuse (NACDA) Workgroup to identify cannabis policy research areas with the greatest urgency and potential for impact, and many of these questions and concerns remain. 

Deadline: See the full notice (linked above) for more details. This notice expires May 5, 2025.

Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)

The purpose of this FOA is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Studies that promote equitable dissemination and implementation of evidence-based interventions among underrepresented communities are encouraged. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (“de-implement”) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. Applications that focus on re-implementation of evidence-based health services (e.g. cancer screening) that may have dropped off amidst the ongoing COVID pandemic are encouraged.

Deadline: Standard dates apply. This opportunity expires May 8, 2025.

Leveraging Health Information Technology (Health IT) to Address and Reduce Health Care Disparities (R01 Clinical Trial Optional)

This FOA seeks to support research that examines the impact of leveraging health information technology (health IT) to reduce disparities in access to and utilization of health care services, quality of care, patient-clinician communication, and health outcomes for populations that experience health disparities in the U.S. Additionally, it seeks to support multidisciplinary research that examines the impact of leveraging health information technology (health IT) to reduce disparities in access to care, quality of care, patient-clinician communication, and health outcomes for populations that experience health disparities in the U.S. Projects should include a focus on one or more NIH-designated health disparity populations in the United States, which include Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asians, Native Hawaiians and Pacific Islanders, socioeconomically disadvantaged populations of any race, underserved rural populations, and sexual and gender minorities living in the 50 states, the District of Columbia, tribal lands, and the U.S. territories. Projects that include populations that identify across more than one population with health disparities are encouraged. Projects should involve collaborations from relevant stakeholders, health disparity population groups such as academic researchers, administrators and leaders of healthcare systems or clinics, clinicians caring for the patients from populations that experience health disparities, and patient advisory and advocacy groups. 

Deadline: Standard dates apply. This opportunity expires May 8, 2025.

NOSI: HEAL Initiative: Workforce Interventions to Improve Addiction Care Quality and Patient Outcomes 

Through the National Institutes of Health (NIH), the Helping to End Addiction Long-Term (HEAL) initiative seeks studies that identify, develop, and/or evaluate strategies to address challenges with recruiting, training, and retaining a robust and highly qualified behavioral health workforce.  Strategies explored through this initiative should focus on increasing recruitment and retention, improving provider training, reducing stigma among providers, increasing access to care and number of patients served, improving quality of care, and/or improving patient outcomes. 

Deadline: See the full notice (linked above) for more details. This notice expires September 8, 2025.

This FOA allows for applications that propose large-scale, complex research projects with multiple highly integrated components focused on a common research question relevant to aging. Such projects will likely involve an integrated multidisciplinary team of investigators within a single institution or a consortium of institutions.

Deadline: Standard dates apply. This opportunity expires September 26, 2025.

NOSI: Research on Addressing Violence to Improve Health Outcomes

The purpose of this NOSI is to highlight interest in addressing the role of violence in health outcomes and integrating violence-related screening and interventions into health care settings. This Notice is to encourage intervention research focused on addressing exposure to violence - including but not limited to child maltreatment, intimate partner violence/teen dating violence, elder mistreatment, peer violence/bullying, and community violence—to improve individual-level health processes and outcomes. This Notice encourages novel intervention research aimed at developing, refining, adapting, and testing interventions focused on preventing violence or addressing acute and chronic effects of violence on physical and behavioral health. Interventions for the treatment and prevention of violence victimization and perpetration across different populations in settings where other health conditions are treated are encouraged. In addition, interventions that seek to translate basic behavioral and social science research findings into innovative treatment approaches are encouraged. Implementation research can elucidate effective strategies for moving evidence-based prevention and treatment approaches into practice. As such, effectiveness, implementation, and hybrid effectiveness-implementation designs are encouraged, as appropriate to the research questions proposed.

Deadline: Standard dates apply. This opportunity expires October 5, 2025.

Clinical Studies of Mental Illness (Collaborative R01) (Clinical Trial Optional)

This FOA seeks to support collaborative clinical studies, that primarily focus on mental health genetics, biomarker studies, and studies of mental illnesses (e.g., psychopathology, neurodevelopmental trajectories of psychopathology). Applicants should apply to this FOA when two or more sites are needed to complete the study. Accordingly, the collaborating studies share a specific protocol across the sites and are organized as such in order to increase sample size, accelerate recruitment, or increase the inclusion of women and minorities ( NOT-OD-18-014) and NIH-defined health disparity populations. It is expected that one site will be submitted as a coordinating R01 for data management and/or other centralized administration. For a linked set of collaborative R01s, each application has its own Program Director/Principal Investigator (PD/PI). The collaborative R01 program provides a mechanism for cross-R01 coordination, quality control, database management, statistical analysis, and reporting.  T his FOA allows for applications that propose large-scale, complex research projects with multiple highly integrated components focused on a common research question relevant to aging. Such projects will likely involve an integrated multidisciplinary team of investigators within a single institution or a consortium of institutions.

Deadline: Standard dates apply. This opportunity expires January 8, 2026.

NIH places a high priority on research with individuals and populations at increased risk for adverse health outcomes, and especially those who have received insufficient attention from the scientific research enterprise. To this end, and in response to Executive Order 14075 on Advancing Equality for Lesbian, Gay, Bisexual, Transgender, Queer, and Intersex Individuals, this notice announces an interest in research on the impact and consequences of family support and family rejection on the health and well-being of sexual and gender minority (SGM, defined for NIH purposes in NOT-OD-19-139) individuals across the life course. Research proposed under this NOSI may include behavioral, social, clinical, implementation, basic, complementary, integrative, and any other relevant research approaches that probe the influences of family rejection, acceptance, affirmation, support, and belonging on the immediate and long-term health and health outcomes of SGM individuals at any life stage. Studies may also include prevention, intervention, and service delivery research that seeks to prevent, reduce, or treat adverse effects associated with family rejection and/or improve or maintain SGM people’s health.

Deadline: See the full notice (linked above) for more details. This notice expires May 8, 2026.

Short-Term Research Education Program to Enhance Diversity in Health-Related Research (R25 Clinical Trial Not Allowed)

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research. This NOFO supports creative educational activities within the mission areas of the NHLBI, with a primary focus on facilitating research experiences for undergraduate students or for medical, dental, nursing, and other health professional students.
Deadline: See the full notice (linked above) for more details. This notice expires August 20, 2026.

The NIAAA will solicit applications to support the secondary analyses of existing data sets with the goal of enhancing our understanding of the following: 1) the patterns and trajectories of alcohol consumption, 2) the epidemiology and etiology, including genetics, of alcohol-related problems and disorders, and 3) alcohol-related health services and health systems, including access, quality, and efficiency. This Notice encourages applications proposing innovative analyses of existing alcohol research data, answering novel research hypotheses and questions, and developing and testing advanced analytical methodologies applicable to alcohol related epidemiological, behavioral and genetics research.

Deadline: See the full notice (linked above) for more details. This notice expires September 6, 2026.

NOSI: Advancing mHealth Interventions for Understanding and Preventing Alcohol-Related Domestic Violence

In light of the documented increases in both alcohol misuse (among some individuals) and domestic violence (DV) as a result of the COVID-19 pandemic and array of mandated restrictions enacted to mitigate the spread of the virus, the purpose of this solicitation is to announce NIAAA’s interest in addressing the need for research related to developing, testing, and intervening proximal to drinking occasions, when risk of DV is elevated, to decrease the likelihood of alcohol consumption at levels sufficient to trigger DV and to provide skills shown to reduce risk of DV perpetration and victimization. In particular, this solicitation seeks to advance the development, feasibility, acceptability, pilot testing, potential efficacy, and implementation of scalable, low resource, and remotely delivered interventions via mobile devices (mHealth) that rely on communication technologies for reducing and preventing alcohol consumption and DV. For this FOA, the term “domestic violence” extends to child maltreatment (abuse and neglect) and elder abuse, in addition to intimate partner violence (IPV). 

Deadline: See the full notice (linked above) for more details. This notice expires September 8, 2026.

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications that will advance translational research to better understand the emergence, trajectory, and outcomes of schizophrenia and related psychotic disorders in mid- to late-life, and to identify targets for future development of prevention and treatment interventions. This NOFO uses the R01 grant mechanism, while the companion NOFO (PAR-24-026), uses the R21 mechanism. Investigators proposing high risk/high reward projects that lack preliminary data may be more appropriate for the R21 mechanism.

Deadline: See the full notice (linked above) for more details. This notice expires September 8, 2026.

Providing Research Education Experiences to Enhance Inclusivity for a Diverse Substance Use and Addiction Scientific Workforce (R25 Clinical Trials Not Allowed)

This R25 Education Program will provide research experiences to prepare individuals from diverse backgrounds to successfully transition to the subsequent professional career stage. This NOFO invites established researchers with a record of NIH funding, who can demonstrate that they have successfully guided previous early career scientists to independent research careers and are able to direct an educational research capacity building program to work with their institutions to submit an application for support. This R25 program is designed to strengthen the pipeline of individuals in biomedical, behavioral, and clinical substance use and addiction research across various stages of the research pipeline to enhance the number of independently funded investigators and help promote diversity and inclusion throughout the research workforce.

Deadline: See the full notice (linked above) for more details. This notice expires November 14, 2026.

NOSI: Data Informed, Place-Based Community-Engaged Research to Advance Health Equity

As we continue to personalize health interventions and move towards precision medicine, location-based metrics have emerged as pivotal tools. These metrics, derived from geospatial data, can provide critical insights into how different aspects of our environments—from air quality to access to healthcare facilities—contribute to our health. Such a geographical lens can highlight the hidden patterns and variations in disease prevalence and health outcomes across different regions or communities. This can enable more targeted and efficient interventions, and allow for the tailoring of prevention and treatment strategies to the unique contexts of specific locations or populations, thereby improving health outcomes and advancing precision medicine, as well as health equity. Given the nature of this research, the NIH encourages the formation of interdisciplinary research teams.

Deadline: See the full notice (linked above) for more details. This notice expires January 8, 2027.

Agency for Healthcare Research and Quality (AHRQ) Announces Interest in Research on Climate Change and Healthcare

This Special Emphasis Notice (SEN) announces AHRQ’s interest in receiving health services research grant applications that address the intersection of climate change and healthcare. Most climate-related health services research to date has focused on the hospital setting. AHRQ continues to welcome hospital-focused applications, but also encourages applications that address other provider types and settings, including primary care, long-term care, mental health, and pharmacy. AHRQ also encourages applications for education, training, and conference grants that propose to develop a strong field of climate-savvy health services researchers. AHRQ encourages research teams to submit applications in response to this SEN using AHRQ’s standing R01, R03, R18, and R13 funding opportunities ( PA-18-793,  PA-18-794,  PA-18-795,  PA-22-238). AHRQ also encourages  training and education applications that propose developing health service research skills through projects that address climate change.

Deadline: Find relevant funding opportunities and their deadlines in the full notice (linked above).

NSF Funding Opportunities:

Smart and Connected Communities (S&CC) 

Communities in the United States (US) and around the world are entering a new era of transformation in which residents and their surrounding environments are increasingly connected through rapidly-changing intelligent technologies. This transformation offers great promise for improved wellbeing and prosperity but poses significant challenges at the complex intersection of technology and society. The goal of the NSF Smart and Connected Communities (S&CC) program solicitation is to accelerate the creation of the scientific and engineering foundations that will enable smart and connected communities to bring about new levels of economic opportunity and growth, safety and security, health and wellness, accessibility and inclusivity, and overall quality of life. This program encourages researchers to work with community stakeholders (e.g., residents, neighborhood or community groups, nonprofit or philanthropic organizations, businesses, as well as municipal organizations) to identify and define challenges they are facing, enabling those challenges to motivate use-inspired research questions. The S&CC program supports integrative research that addresses fundamental technological and social science dimensions of smart and connected communities and pilots solutions together with communities. Importantly, this program is interested in projects that consider the sustainability of the research outcomes beyond the life of the project, including the scalability and transferability of the proposed solutions.

Deadline: April 1, 2024.

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Other Funding Opportunities:

RWJF Pioneering Ideas: Exploring the Future to Build a Culture of Health

This funding opportunity seeks proposals primed to impact health equity moving forward. We are interested in ideas that address any of these four areas of focus: Future of Evidence; Future of Social Interaction; Future of Food; Future of Work. Additionally, we welcome ideas that might fall outside of these four focus areas, but which offer unique approaches to advancing health equity and our progress toward a Culture of Health. We want to hear from scientists, anthropologists, artists, urban planners, community leaders—anyone, anywhere who has a new or unconventional idea that could alter the trajectory of health and improve health equity and wellbeing for generations to come. The changes we seek require diverse perspectives and cannot be accomplished by any one person, organization, or sector. Brief proposals must be submitted first; full proposals are by invitation only. 

Deadline: Letters of Inquiry (LOIs) are accepted anytime.